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KMID : 0616120120430010054
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Korean Journal of Pharmacognosy
2012 Volume.43 No. 1 p.54 ~ p.58
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Anti-fatigue and Hepatoprotective Effects of Fermented Antler
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Shim Joo-Won
Kim Dong-Hyun
Kim Nam-Jae
Kim Young-Su
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Abstract
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To increase the extraction yield and biological effect of antler by fermentation, probiotics fermenting antler were screened from rice shells. Of screened Bacillus species, the most potently antler-degrading probiotics was Bacillus KH-07. The supernatant yield of fermented antler is highest. Bacillus KH-07 may belong to Bacillus licheniformis by biochemical and 16S rDNA sequencing analyses. The KH-07-fermented antler (50 mg/kg) increased the anti-fatigue effect 2.3-fold compared to that of non-treated antler. Furthermore, the KH-07-fermented antler improved CCl₄-induced liver injury in mice. Based on these findings, the extraction yield and biological effect of antler can be increased by KH-07 fermentation.
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KEYWORD
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Antler, Fermentation, Fatigue, Bacillus licheniformis
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